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r r r r 产品名称:r | r r 螺内酯r | r
r r r CAS:r | r r 52-01-7r | r
r r r 标准:r | r r EPr | r
r r r 有无证:r | r r 有证r | r
r r r 天然/合成:r | r r 合成r | r
r r r 级别:r | r r 医药级r | r
r r r 含量:r | r r 99%r | r
r r r 外观:r | r r 白色粉状r | r
r r r 包装:r | r r 20KG/纸板桶 可拆分r | r
r r r 成份:r | r r 17β-羟基-3-氧代-7α-(乙酰硫基)-17α-孕甾-4-烯-21-羧酸γ-内酯r | r
r r r 理化属性:r | r r 白色或类白色的细微结晶性粉末;有轻微硫醇臭。本品在三氯甲烷中极易溶解,在苯或乙酸乙酯中易溶,在乙醇中溶解,在水中不溶。r | r
r r r 类别:r | r r 医药原料r | r
r r r 行业:r | r r 医药r | r
r r r 领域:r | r r 利尿药r | r
r r r 下延产品:r | r r 螺内酯片 螺内酯胶囊r | r
r r r 运用:r | r r 拮抗醛固酮的排钾保钠作用,促进Na+和水的排出,肾衰竭及血钾偏高者禁用r | r
r r r 用法用量:r | r r 1.成人 ①治疗水肿性疾病,每日40~120mg,分2~4 次服用,至少连服5日。以后酌情调整剂量。 ②治疗高血压,开始每日 r40~80mg,分次服用,至少2周,以后酌情调整剂量,不宜与血管紧张素转 换酶抑制剂合用,以免增加发生高钾血症的机会。 ③治疗原发性醛固酮增 r多症,手术前患者每日用量100~400mg,分2~4次服用。不宜手术的患者, 则选用较小剂量维持。 ④诊断原发性醛固酮增多症。长期试验,每日400mg, r分2~4次,连续3~4周。短期试验,每日400mg,分2~4次服用,连续4 日。老年人对本药较敏感,开始用量宜偏小。 r2.小儿:治疗水肿性疾病,开始每日按体重1~3mg/kg或按体表面积30~90mg/m2,单次或分2~4次服用,连服5日后酌情调整剂量。最大剂量为每日3~9mg/kg或90~270mg/m2。r | r
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